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	DEFINITION
	PHYSIOLOGY OF CALCIUM HOMEOSTASIS
	REGULATION OF THE PRODUCTION AND ACTION OF HUMORAL MEDIATORS OF CALCIUM HOMEOSTASIS
	Parathyroid Hormone
	Vitamin D
	Parathyroid Hormone Relation Peptide (PTHrP)
	Mediators of Bone Remodeling
	HYPERCALCEMIC DISORDERS
	Endocrine Disorders Associated with Hypercalcemia
	Malignancy- Associated Hypercalcemia
	Inflammatory Disorders Causing Hypercalcemia
	Disorders of Uncertain Etiology
	Medication-Induced Hypercalcemia
	CLINICAL ASSESSMENT OF THE HYPERCALCEMIC PATIENT
	History and Physical Examination
	Laboratory Examination
	Management