Full-spectrum cannabis contains over 100 phytocannabinoids, each with varying ratios that can affect the user’s experience. Understanding these ratios can help predict the effects of cannabis and aid in finding a personalized dosage.
Before THC was identified as the cannabinoid responsible for producing a “high,” landrace cultivars had more balanced cannabinoid ratios, according to Cannacraft co-founder Dennis Hunter. However, as strains were bred to contain higher amounts of THC, CBD levels decreased.
In 2008, the first cannabis testing lab opened in the United States, allowing for modernized testing and research on cannabinoids. Early pioneers in CBD include Fred Gardner and Martin Lee, who worked with grower Wade Laughter to start Project CBD and create Harlequin, one of the earliest CBD-rich cultivars.
Cannabinoid ratios can produce different outcomes based on their concentration. For example, a 1:1 ratio of CBD to THC is equal parts of each cannabinoid and is commonly found in various cannabis products, making it an excellent starting point for individuals new to THC. Additionally, this ratio may also be beneficial for pain management as both THC and CBD act as analgesics using different mechanisms in the body.
Low CBD to THC ratios such as 2:1, 3:1, and 4:1 have similar effect profiles with minimal euphoria from THC and more medical benefits from CBD. These ratios are excellent for pain management and can be used for numerous conditions such as cancer or skin conditions like eczema.
High CBD to THC products typically contain ratios starting at 8:1 up to 40:1 and are unlikely to produce feelings of intoxication even at higher doses. Ratios above 18:1 CBD to THC are commonly used in cases of pediatric epilepsy as they do not produce intoxication.
Research on cannabinoid ratios primarily focuses on a 1:1 balance of THC and CBD, as well as high CBD:THC ratios for epilepsy. The research on high CBD:THC ratios for epilepsy has shown that CBD is beneficial for some types of epilepsy in some people.
It’s essential to consider the more than 100 other phytocannabinoids, as well as terpenes and other chemicals such as alkaloids, when determining cannabinoid ratios. For example, CBN may have benefits for sleep, along with CBD and THC.
In conclusion, understanding cannabinoid ratios can help predict the effects of cannabis and aid in finding a personalized dosage. Researchers are continuing to study various cannabinoid ratios and their potential health benefits.